Dr Ace North

Research Interests

I study the ecological and evolutionary dynamics of populations, often with an emphasis on the role of spatial structure. I'm interested in all kinds of populations, yet currently I am focussed on malaria-spreading mosquitoes. In particular, I am researching how transgenic elements might be driven into mosquito populations to reduce their efficiency in transmitting malaria.
I use a mixture of mathematical and statistical models. Mathematical models are useful for addressing hypothetical questions, such as how will a mosquito population respond if a particular insecticide is applied in a given way. Statistical models help us to understand the fluctuations in mosquito abundance observed by field researchers.

Contact Details

Selected Publications

AR North, HCJ Godfray, Modelling the persistence of mosquito vectors of malaria in Burkina Faso, 2018 Malaria journal 17 (1), 140

B Lambert, AR North, A Burt, HCJ Godfray, The use of driving endonuclease genes to suppress mosquito vectors of malaria in temporally variable environments, 2018 Malaria journal 17 (1), 154

L Facchinelli, AR North, CM Collins, M Menichelli, T Persampieri, A Bucci, R Spaccapelo, A Crisanti, MQ Benedict, Large-cage assessment of a transgenic sex-ratio distortion strain on populations of an African malaria vectors, 2019 Parasites & vectors 12 (1), 70

The dynamics of disease in a metapopulation: The role of dispersal range, AR North, HCJ Godfray, Journal of theoretical biology 418, 57-65, 2017                       

The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito, AM Hammond, K Kyrou, M Bruttini, A North, R Galizi, X Karlsson, N Kranjc, et al., PLoS genetics 13 (10), e1007039, 2017                  

How driving endonuclease genes can be used to combat pests and disease vectors. HCJ Godfray, A North, A Burt, BMC biology 15 (1), 81, 2017           

The use of sequential mark-release-recapture experiments to estimate population size, survival and dispersal of male mosquitoes, PS Epopa, AA Millogo, CM Collins, A North, F Tripet, MQ Benedict, et al., Parasites & vectors 10 (1), 376, 2017

Modelling the spatial spread of a homing endonuclease gene in a mosquito population, A North, A Burt, HCJ Godfray, Journal of Applied Ecology 50 (5), 1216-1225, 2013

Modelling the control of mosquito-borne diseases, North, A. and Hancock, P., In 'Ecology of parasite-vector interactions' (eds W. Takken and C.J.M. Koenraadt) Wageningen Academic Pub., 2012

Local adaptation in a changing world: The roles of gene-flow, mutation, and sexual reproduction, North, A., Pennanen, J., Ovaskainen, O. and Laine, A-L., Evolution Volume 65, Issue 1, pages 79–89, January 2011

Evolutionary responses of dispersal distance to landscape structure and habitat loss, North, A., Cornell, S. and Ovaskainen, O., Evolution Volume 65, Issue 6, pages 1739–1751, June 2011

Interactions between dispersal, competition, and landscape heterogeneity, North, A. and Ovaskainen, O., Oikos, Volume 116, Number 7, July 2007