Shimeld Lab

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Shimeld Lab

About the Group

We use approaches drawn from genomics, developmental biology and evolutionary biology to determine how the complexity of animal bodies forms during embryo development, and to understand how the diversity of animal body plans has evolved. The origins of complexity in nervous systems are a particular focus, where we seek to examine both how cell types develop and evolve, how they are organised in the embryo, and how stem cells are managed to control how many cells an organism has.  

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Recent Publications

Bao, Y., Xu, F. and Shimeld, S.M. (2017). Phylogenetics of Lophotrochozoan bHLH Genes and the Evolution of Lineage-Specific Gene Duplicates. Genome biology and evolution 9 (4), 869-886

Li, G., Liu, X., Xing, C., Zhang, H., Shimeld, S.M. and Wang, Y. (2017). Cerberus–Nodal–Lefty–Pitx signaling cascade controls left–right asymmetry in amphioxus. Proceedings of the National Academy of Sciences, 201620519

Sutton, E.R., Yu, Y., Shimeld, S.M., White-Cooper, H. and Alphey, L. (2016). Identification of genes for engineering the male germline of Aedes aegypti and Ceratitis capitata. BMC genomics 17, 948.

Patthey, C., Clifford, H., Haerty, W., Ponting, C.P., Shimeld, S.M. and Begbie, J. (2016). Identification of molecular signatures specific for distinct cranial sensory ganglia in the developing chick. Neural Dev. 2016; 11: 3

Sato A, Kawashima T, Fujie M, Hughes S, Satoh N, and Shimeld, S.M. (2015). Molecular basis of canalization in an ascidian species complex adapted to different thermal conditions. Scientific Reports, 5:16717.

Kenny, N., Namigai, E., Marletaz, F., Hui, J. and Shimeld, S.M. (2015). Draft genome assemblies and predicted microRNA complements of the intertidal lophotrochozoansPatella vulgata (Mollusca, Patellogastropoda) and Spirobranchus (Pomatoceros) lamarcki (Annelida, Serpulida). Marine Genomics, 24:139-146.