Dr Odile Harrison

Research Interests

My work explores the population genomics of bacterial pathogens. I am particularly interested in defining bacterial lineages using genome data as this has the potential to allow strains associated with distinct pathologies including antimicrobial resistance to be more rapidly identified. Such information brings with it opportunities for improving diagnostics, preventing infection through vaccination and the capacity to limit antimicrobial resistance. My research involves the analysis of whole genome sequence data belonging to the sexually transmitted pathogens Neisseria gonorrhoeae and Chlamydia trachomatis as well as the meningitis causing pathogens Neisseria meningitidis, Haemophilus influenzae and Streptococcus agalactiae.

 

I am an editorial board member for the Journal of Infection and a fellow of the Higher Education academy.

Publications
  • The global meningitis genome partnership.

  • Pan-GWAS of Streptococcus agalactiae Highlights Lineage-Specific Genes Associated with Virulence and Niche Adaptation.

  • Localized Hypermutation is the Major Driver of Meningococcal Genetic Variability during Persistent Asymptomatic Carriage.

  • Association of Neisseria gonorrhoeae Plasmids With Distinct Lineages and The Economic Status of Their Country of Origin.

  • Neisseria gonorrhoeae population genomics: use of the gonococcal core genome to improve surveillance of antimicrobial resistance.

  • Plasmids in Neisseria gonorrhoeae are associated with distinct lineages and economic status of their country of origin

  • Complete genome and methylome analysis of Neisseria meningitidis associated with increased serogroup Y disease.

  • Genetic determinants of genus-level glycan diversity in a bacterial protein glycosylation system.

  • More
Graduate Students
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