I trained in medicine at Cambridge and Oxford, and worked as a clinician in medicine, paediatrics, and general practice in the UK and Africa before more formal research training with an MSc in Epidemiology at the London School of Hygiene and Tropical Medicine. I have undertaken research in the National Perinatal Epidemiology Unit, Oxford, the Oxford Vaccine Group, Oxford, the Kenya Medical Research Unit, Kilifi, Kenya, the Medical Research Council Unit, The Gambia, the Malawi-Liverpool-Wellcome Trust Research Programme, Blantyre, Malawi and two periods of time working with Professor Martin Maiden in the Department of Zoology, Oxford, where I am currently a senior researcher.
The main focus of my research has been in vaccination against meningococcal disease, immunological memory, risk factors for carriage and transmission of Neisseria meningitidis, and the effects of vaccination on carriage. I am also interested in the role of non-pathogenic Neisseria species in the development of natural immunity against Neisseria meningitidis. Other research interests include understanding transmission and immunity against Non-typhoidal salmonella.