Oliver Pybus

Oliver Pybus

Royal Society University Research Fellow, University Lecturer (elect) in Evolutionary Biology

Tutor in Biology, New College

 

Research Interests

My research aims to explain the evolutionarykjjhgjgkhj dynamics of pathogens, particularly viral infections of humans, including HIV/AIDS, the Hepatitis C Virus, and Influenza. I hope to understand how evolutionary and ecological processes - which occur on the same timescale for many pathogens - combine and interact in natural populations.

Other Interests

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Contacts

Email: oliver.pybus@zoo.ox.ac.uk
Phone: 01865 271274
 

Websites

 

Selected Publications

  • Katzourakis A, Gifford RJ, Tristem M, Gilbert MTP, Pybus OG. 2009. The macroevolution of complex retroviruses. Science In press.
  • Pybus OG & Rambaut A. 2009. Evolutionary analysis of the dynamics of viral infectious disease. Nature Reviews Genetics In press
  • Kawashima Y, Pfafferott K, Frater J, Matthews P et al. 2009. Adaptation of HIV-1 to human leukocyte antigen class I. Nature 458:641-5
  • Pybus OG, Barnes E, Taggart R, Lemey P et al. 2009. The genetic history of the hepatitis C virus in East Asia. Journal of Virology 83:1071-82
  • Smith GJD, Vijaykrishna D, Bahl J, Lycett SJ, Worobey M, Pybus OG et al. 2009. Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic. Nature 459:1122-5
  • Gifford, RJ, Katzourakis A, Tristem M, Pybus OG et al. 2008. A transitional endogenous lentivirus from the genome of a basal primate and implications for lentivirus evolution. Proc. Natl. Acad. Sci. USA 105:20362-7
  • Rambaut A, Pybus OG, Nelson MI, Viboud C et al. 2008. The genomic and epidemiological dynamics of human influenza A virus. Nature 453:615-9
  • Recker M, Pybus OG, Nee S, Gupta S. 2007. The generation of influenza outbreaks by a network of host immune responses against a limited set of antigenic types. Proc. Natl. Acad. Sci. USA 104:7711-6
  • Pybus OG, Rambaut A, Belshaw R, Freckleton RP et al. 2007. Phylogenetic estimation of deleterious mutation load in RNA viruses and its contribution to viral evolution. Molecular Biology & Evolution 24:845-52
  • atzourakis A, Tristem M, Pybus OG, Gifford RJ. 2007. Discovery and analysis of the first endogenous lentivirus. Proc. Natl. Acad. Sci. USA 104:6261-5
  • Fraser C, Donnelly CA, Cauchemez S, Hanage WP et al. 2009. Pandemic potential of a novel strain of influenza A (H1N1): early findings. Science 324:1557-61