Oliver Pybus

Professor of Evolution & Infectious Disease

Professorial Fellow, New College


Research Interests

My research aims to explain the evolutionary dynamics of pathogens, particularly viral infections of humans, including HIV/AIDS, the Hepatitis C Virus, and Influenza. I hope to understand how evolutionary and ecological processes - which occur on the same timescale for many pathogens - combine and interact in natural populations.



Email: oliver.pybus@zoo.ox.ac.uk



Selected Publications

  • Faria NR et al. (2014) The hidden history of HIV-1: establishment and early spread of the AIDS pandemic. Science 346:56-61

  • Wikramaratna P, Pybus OG & Gupta S (2014) Contact between bird species of different lifespans can promote the emergence of highly pathogenic avian influenza strains. Proceedings of the National Academy of Sciences USA 111:10767-72

  • Pybus OG, Gray RR (2013) The virus whose family expanded. Nature 498:310-11

  • Lam TT et al. (2013) The genesis and source of the H7N9 influenza viruses causing human infections in China. Nature 502:241-4

  • Pybus OG et al. (2012) Unifying the spatial epidemiology and molecular evolution of emerging epidemics. Proceedings of the National Academy of Sciences USA 109:15066-71

  • Farci P et al. (2012) Profibrogenic chemokines and viral evolution predict rapid progression of hepatitis C to cirrhosis. Proceedings of the National Academy of Sciences USA 109:14562–7

  • Vijaykrishna D et al.  (2011) Long-term evolution and transmission dynamics of swine influenza A virus. Nature 473:519-22

  • Katzourakis A et al. (2009) Macroevolution of complex retroviruses. Science 325:1512

  • Fraser C et al. (2009) Pandemic potential of a novel strain of influenza A (H1N1): early findings. Science 324:1557-61

  • Smith GJ et al. (2009) Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic. Nature 459:1122-5

  • Kawashima Y et al. (2009) Adaptation of HIV-1 to human leukocyte antigen class I. Nature 458:641-45

  • Pybus OG & Rambaut A (2009) Evolutionary analysis of the dynamics of viral infectious disease. Nature Reviews Genetics 10:540-50

  • Rambaut A  et al. (2008) The genomic and epidemiological dynamics of human influenza A virus. Nature 453:615-9