My research interests focus on the various evolutionary processes that have shaped genomes. My current focus is on viral evolution and in particular, endogenous retroviruses (ERVs) that constitute a substantial fraction of vertebrate genomes. I am interested in understanding the circumstances under which ERVs successfully colonize genomes, using structured models to gain insight into the dynamics of this evolutionary process.
Kanda RK, Coulson T (2015) The effect of life history on retroviralgenome invasions. PloS ONE 10 (2), e0117442
Lee A, Huntley D, Aiewsakun P, Kanda RK, Lynn C, Tristem M (2014) Novel Denisovan and Neanderthal Retroviruses. Journal of Virology, 88(21):12907-9
Jones M, Frampton D, Dry I, Singh M, Kanda RK, Kellam P, Hollinshead M, Kinchington P, O’Toole EA & Breuer J (2014) RNAseq analysis of host and viral gene expression highlights interaction between Varicella zoster virus and keratinocyte differentiation. PLoS Pathogens DOI: 10.1371/journal.ppat.1003896
Kanda RK, Tristem M & Coulson T (2013) Exploring the effects of immunity and life history on the dynamics of an endogenous retrovirus. Philos Trans R Soc Lond B Biol Sci. 368:1626
Depledge DP, Palser AL, Watson SJ, Lai IY, Gray ER, Grant P, Kanda RK, Leproust E, Kellam P & Breuer J (2011) Specific capture and whole-genome sequencing of viruses from clinical samples. PLoS One 6(11): e27805
Kanda RK, Quinlivan ML, Gershon AA, Nichols RA & Breuer J (2011) Population diversity in batches of the varicella Oka vaccine. Vaccine 29(17): 3293-3298
Bussell JJ, Pearson NM, Kanda RK, Filatov DA & Lahn BT (2006) Human polymorphism and human-chimpanzee divergence in pseudoautosomal region correlate with local recombination rate. Gene 368:94-100