My research interests focus on the various evolutionary processes that have shaped genomes. My current focus is on viral evolution and in particular, endogenous retroviruses (ERVs) that constitute a substantial fraction of vertebrate genomes. I am interested in understanding the circumstances under which ERVs successfully colonize genomes, using structured models to gain insight into the dynamics of this evolutionary process.
Lee A, Huntley D, Aiewsakun P, Kanda RK, Lynn C, Tristem M (2014) Novel Denisovan and Neanderthal Retroviruses. Journal of Virology, 88(21):12907-9
Jones M, Frampton D, Dry I, Singh M, Kanda RK, Kellam P, Hollinshead M, Kinchington P, O’Toole EA & Breuer J (2014) RNAseq analysis of host and viral gene expression highlights interaction between Varicella zoster virus and keratinocyte differentiation. PLoS Pathogens DOI: 10.1371/journal.ppat.1003896
Kanda RK, Tristem M & Coulson T (2013) Exploring the effects of immunity and life history on the dynamics of an endogenous retrovirus. Philos Trans R Soc Lond B Biol Sci. 368:1626
Depledge DP, Palser AL, Watson SJ, Lai IY, Gray ER, Grant P, Kanda RK, Leproust E, Kellam P & Breuer J (2011) Specific capture and whole-genome sequencing of viruses from clinical samples. PLoS One 6(11): e27805
Kanda RK, Quinlivan ML, Gershon AA, Nichols RA & Breuer J (2011) Population diversity in batches of the varicella Oka vaccine. Vaccine 29(17): 3293-3298
Bussell JJ, Pearson NM, Kanda RK, Filatov DA & Lahn BT (2006) Human polymorphism and human-chimpanzee divergence in pseudoautosomal region correlate with local recombination rate. Gene 368:94-100